In this novel, the protagonist, a young, ordinary man, visits his cousin at a tuberculosis sanatorium in the Swiss Alps. Intending to stay for only a few weeks, he ends up remaining there for seven years, becoming a patient himself. The book explores his experiences and relationships with other patients and staff, delving into philosophical discussions on life, time, and the nature of disease. It also provides a vivid portrayal of the European society and intellectual life on the eve of World War I.

The novel presents a poignant exploration of a man's struggle with his dual nature. The protagonist, a middle-aged man, finds himself torn between his humanistic, intellectual tendencies and his more primitive, wolf-like instincts. As he navigates his way through the surreal and sometimes hallucinatory world, he encounters various characters who challenge his views and push him towards self-discovery and transformation. The narrative delves into themes of alienation, the subconscious mind, and the search for meaning in life.

The novel is a reimagining of the Faust legend set in the context of the first half of the 20th century and the turmoil of Germany in that period. It tells the story of a composer who makes a pact with the devil, exchanging his soul for unlimited creative genius. The protagonist's life and work reflect the cultural and political journey of Germany leading up to World War II, providing a deep exploration of the individual's role in a society undergoing dramatic change. The novel is also a profound meditation on the nature of time, the art and the artist, and the destructiveness of human ambition.