"Dinner at the Homesick Restaurant" is a novel about the life of the Tull family, which is marked by abandonment and discord, but also love and resilience. The story is told from the perspective of each family member, providing a unique viewpoint on the family's dynamics and history. The matriarch, Pearl, struggles to raise her three children, Cody, Ezra, and Jenny, after their father abandons them. Each child deals with the abandonment and their dysfunctional family in different ways, shaping their adult lives. The novel explores themes of family, love, abandonment, and the idea of home.

Set in early 20th century Baltimore, the novel follows the life of Miss Susie Slagle, a boarding house owner who rents out rooms to medical students. The narrative is full of colorful characters, including the students themselves, who bring their own unique stories and perspectives. The book provides a vivid depiction of the time period, exploring topics such as gender roles, class distinctions, and the challenges and triumphs of pursuing a medical career.

In "Searching for Caleb," a quirky, upper-class family is brought to life, with a focus on the Peck family's black sheep, Duncan. Duncan, who rejects the family's traditions and expectations, embarks on a quest to find his missing uncle Caleb, who disappeared decades ago without a trace. Alongside him is his cousin, Justine, who also feels out of place within their family. The novel explores themes of identity, family bonds, and the need for personal freedom.