This novel is a contemporary, multicultural exploration of family life, love, and identity. It follows the lives of two mixed-race families, the Belseys and the Kipps, who are linked by their shared professions in academia and a complex web of marital and extramarital relationships. The story is set against the backdrop of Wellington, a fictional New England town, and explores themes of race, class, and cultural clash. It also delves into the world of academia, examining the politics and conflicts that arise in that environment.

The novel explores the life of Hannah Easton, a woman born in 17th century Salem, who gets married to a British adventurer and travels to India. In India, she becomes the concubine of a local ruler and takes on the name "The Holder of the World". The story is narrated by a 20th-century woman who discovers Hannah's story through a virtual reality device. The narrative weaves together the historical and the contemporary, the East and the West, and the real and the virtual, to create a rich tapestry of a woman's life and the cultural clashes she experiences.

The novel is a layered narrative that alternates between the protagonist, a writer, working on his novel in 1960s New Hampshire and the story within his novel set in 1930s New England. The protagonist's story explores his relationships with his family, friends, and fellow writers, while the story within the novel follows a young man's journey of self-discovery during the Great Depression. The book won the National Book Award for Fiction in 1975.