The novel is a postmodern exploration of death and consumerism in the United States. It follows a year in the life of Jack Gladney, a professor who has made his name by pioneering the field of Hitler Studies at a small liberal arts college in Middle America. Jack and his fourth wife, Babette, are afraid of death and are obsessed with finding a cure for their fear. Their lives are disrupted by an airborne toxic event, which forces them to confront their mortality and the toxic effects of modern life.

"Women" is a semi-autobiographical novel that explores the chaotic love life of an aging writer. The protagonist, a hard-drinking and crude poet, navigates through a series of relationships with a variety of women, each with their own eccentricities and troubles. The narrative delves into the gritty, often sordid details of these relationships, depicting the protagonist's struggle with his own demons and the complexities of his romantic entanglements. Despite the seemingly bleak tone, the novel is punctuated with moments of raw humor and profound insight into human nature.

"Bad News" is the second novel in a series that follows the life of Patrick Melrose, a man from a wealthy but deeply troubled family. In this installment, Patrick, now 22, must travel to New York to collect his father's ashes. As he navigates the city, he struggles with his addiction to drugs and alcohol, and grapples with the traumatic memories of his abusive father. The narrative provides a darkly comic and deeply poignant exploration of addiction, trauma, and the struggle for redemption.

"Some Hope" is a darkly humorous novel that delves into the life of a man who struggles to overcome his traumatic past and drug addiction. He is invited to a lavish party filled with Britain's aristocracy, where he must confront his past and deal with the pretentious and shallow society he is part of. The narrative explores themes of abuse, recovery, and the struggle to find redemption and hope amidst despair.