The novel follows the life of Patrick Melrose, a man battling with his drug addiction and his troubled relationship with his parents. Patrick tries to come to terms with his mother’s decision to leave her estate to a New Age foundation rather than to him, her only son. The story delves into the complexities of inheritance, parenthood, and the lasting impact of childhood trauma. The narrative shifts between the perspectives of Patrick, his wife, and their two young sons, providing a multi-dimensional view of the family's struggles.

"Dept. of Speculation" follows the story of a woman navigating her life as a writer, a wife, and a mother. The novel explores her journey through marriage, motherhood, and the struggles of maintaining her own identity amidst these roles. It also delves into the hardships of dealing with infidelity and the complexities of love and relationships. The narrative is presented in fragmented pieces, reflecting the protagonist's scattered thoughts and emotions.

This novel explores the complex relationship between a Chinese-American woman and her immigrant mother, who is suffering from dementia. As the mother's condition worsens, her daughter discovers a manuscript written in Chinese that reveals her mother's traumatic past and the true identity of her grandmother - a renowned bonesetter in China. The narrative oscillates between contemporary San Francisco and early 20th century China, illustrating the enduring power of family bonds, the weight of cultural heritage, and the profound impact of past events on present lives.

All My Puny Sorrows is a poignant exploration of the complex relationship between two sisters, one a successful concert pianist battling severe depression and the other a struggling writer trying to support her. The narrative delves into themes of mental illness, suicide, love, and the power of familial bonds. It grapples with the moral and ethical questions surrounding assisted suicide, the struggle to understand a loved one's pain, and the lengths to which one might go to help them find peace.

This novel explores the lives of two former radicals from the 1970s who are now living under assumed identities. The narrative interweaves their past and present, revealing the consequences of their actions and the lengths they must go to keep their secrets. The story is also interjected with the perspective of the woman's son, who is on a quest to uncover his mother's past, adding another layer of intrigue and complexity.

"A Girl Is A Half Formed Thing" is a powerful and experimental novel that delves into the psyche of a young woman as she navigates through a tumultuous and abusive childhood, her complex relationship with her mentally and physically disabled brother, and her own journey towards self-discovery and identity. Written in a unique stream-of-consciousness style, the book explores themes of trauma, sexuality, religion, and resilience, offering a raw and unflinching portrayal of the human experience.

"The Position" is a novel that explores the impact of a bestselling sex manual, written by a couple, on their four children. The book, published in the 1970s, includes explicit illustrations of the couple and becomes a cultural phenomenon. The narrative, spanning over three decades, delves into the lives of the children, their struggles with their parents' public sexual revelations, and how it affects their own relationships and identities as they grow into adulthood.