Nemesis by Philip Roth

Set in Newark, New Jersey, during a polio outbreak in the 1940s, the book follows a dedicated playground director, Bucky Cantor, who remains on duty while many others flee the city. Despite his efforts to keep the children safe, polio begins to affect those around him. As fear and panic spread through the community, Bucky also becomes infected and loses his eyesight. The story is a profound exploration of personal responsibility, duty, and the random, tragic nature of life.