Herzog by Saul Bellow
Herzog is a novel set in 1964, in the United States, and is about the midlife crisis of a Jewish man named Moses E. Herzog. He is just emerging from his second divorce, this one particularly acrimonious. He has two children, one by each wife, who are growing up without him present. His career as a writer and as an academic has stalled. He is currently in a relationship with a vibrant woman, Ramona, but finds himself running away from commitment.