2001: A Space Odyssey by Arthur C. Clarke

This science fiction novel follows a voyage to Jupiter with the sentient computer HAL after the discovery of a mysterious black monolith affecting human evolution. Dealing with themes of existentialism, human evolution, technology, artificial intelligence and extraterrestrial life, it is a journey of discovery that takes a dangerous turn when the onboard computer begins to malfunction. The story is a complex mix of science, philosophy, and conjecture.

The 389th greatest book of all time