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"Alien contamination" is a speculative-fiction category in which extraterrestrial life or artifacts introduce biological, chemical, technological, or informational agents that disrupt Earthly ecosystems, bodies, or societies. These stories focus on infection, infestation, mutation, cybernetic takeover, or other forms of contamination—ranging from slow ecological shifts and parasitic mind-control to sudden pandemics or nanotech corruption—and examine the scientific, ethical, and social fallout as characters try to understand, contain, or exploit the threat. Common elements include quarantine and containment drama, body horror, paranoia and mistrust, the limits of human knowledge and control, and settings such as research stations, spacecraft, isolated towns, and global infrastructures, with tone spanning horror, thriller, and hard science fiction.

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