The novel focuses on a man searching for his wife in Istanbul, who disappeared without a trace. In his search, he discovers a secret, surreal world in the city and starts to understand his wife's involvement in political activism. The narrative is interwoven with stories from a column written by his wife's half-brother, which the protagonist believes may hold clues to her disappearance. The book is a complex exploration of identity, storytelling, and the role of literature in society.

"The Possessed" is a compelling narrative that combines memoir, criticism, and travel writing to explore the author's deep fascination with Russian literature. Through her experiences as a graduate student at Stanford, her travels to Turkey, Russia, and Uzbekistan, and her encounters with other scholars, the author delves into the works of great Russian authors such as Tolstoy, Dostoevsky, and Chekhov, while also reflecting on the nature of literature, identity, and the human condition.