The novel tells the story of a wolf-dog hybrid named White Fang, who endures harsh conditions in the Yukon during the 19th-century Klondike Gold Rush. The narrative follows White Fang's journey from a life in the wild to domestication. He experiences cruelty and brutality from both nature and humans, but eventually finds kindness and compassion with a man who rescues him from a dog-fighting ring. The book explores themes of survival, nature versus nurture, and redemption.

In "Man Meets Dog," the author explores the deep bond between humans and dogs, tracing the origins and development of this unique relationship. Through a combination of personal anecdotes and scientific insights, the book delves into various aspects of canine behavior, psychology, and the evolutionary factors that have shaped the human-dog partnership. The author, an eminent ethologist, uses his observations of his own dogs to illustrate broader themes about communication, affection, and the instinctual basis of domestication, offering readers a thoughtful reflection on why dogs hold such a special place in human society.

On a distant, surreal world, tiny human-like beings live under the control of towering, long-lived alien masters who treat them as pets, pests and curiosities; one young captive learns the aliens’ language and science, sparks an awakening among his people, organizes resistance and technological progress, and forces both species to confront questions of power, freedom and coexistence.