The novel explores the final hours of the Roman poet Virgil, who, while on his deathbed, contemplates the value and impact of his life's work, particularly his unfinished epic, the Aeneid. The narrative is a complex, stream-of-consciousness meditation on art, life, and death, with Virgil wrestling with his desire to burn his epic and the emperor's command to preserve it. The book delves into themes of the meaning of human existence, the role of art in society, and the clash between the individual's inner world and the external world.

The novel delves into the inner life of Joana, a young woman with a complex and introspective nature, as she navigates the vicissitudes of her existence. Through a non-linear narrative and a stream-of-consciousness technique, the reader is immersed in Joana's thoughts and experiences, ranging from her childhood to her adult relationships, including her marriage to Otávio. The protagonist's search for meaning and understanding of her own identity unfolds in poetic and philosophical reflections, revealing the struggles of self-discovery and the desire to transcend the ordinary, bringing her metaphorically 'near to the wild heart' of life itself.