The book follows the life of Calliope Stephanides, a Greek-American hermaphrodite, who narrates her epic story starting from her grandparents' incestuous relationship in a small village in Asia Minor to her own self-discovery in 20th century America. The novel delves into themes of identity, gender, and the American dream, while also providing a detailed history of Detroit through the eyes of three generations of an immigrant family.

The novel is a final look into the life of Harry "Rabbit" Angstrom, a former high-school basketball star, now in his mid-fifties, overweight and grappling with several health issues. Despite his success in business, his personal life is in shambles, with his wife addicted to alcohol and his son to drugs. Harry, struggling with his mortality, is trying to understand his past and make sense of his future, while dealing with the changing American society and the consequences of his own choices.

"A Visit from the Goon Squad" is an interconnected collection of stories about a group of characters whose lives intersect in the music industry. The narrative spans several decades, tracing the characters' journey from their youth to middle age. It explores themes of time, change, and the impact of technology on human relationships and the music industry. The novel is known for its experimental structure, including a chapter written as a PowerPoint presentation.

The novel follows the life of Daisy Goodwill Flett, a seemingly ordinary woman, from her birth in Canada in 1905 to her death. It explores her experiences as a mother, wife, and widow, as well as her work as a gardener and her later years as a columnist. The book is unique in that it is written in a variety of styles including letters, diary entries, and third-person narrative, and it explores themes of identity, love, and the often overlooked lives of women.

The novel centers around a woman named Amber who unexpectedly arrives and disrupts the lives of the Smart family while they are on summer holiday in Norfolk. Each family member - Eve, a writer, Michael, a university professor, and their children Astrid and Magnus - experience unique interactions with Amber, causing them to question their own realities. The mysterious woman's influence forces the family to confront their secrets, insecurities, and the false narratives they've created about themselves.