The book is a darkly comedic and sprawling tale of a rural American outcast, whose life is marked by relentless misfortune and societal marginalization. The protagonist, with an extraordinary talent for animal husbandry, finds himself in constant conflict with the small-minded townsfolk and corrupt officials of his Midwestern community. His journey is one of epic struggle against adversity and the pettiness of small-town politics, culminating in a dramatic and chaotic rebellion that upends the social order of his world. The narrative weaves a rich tapestry of rural life, exploring themes of revenge, social injustice, and the quest for personal redemption.

This novel is a satirical take on academic life, set in a Midwestern agricultural university known as "Moo U." The story weaves together the lives of faculty, students, and university staff, exploring their ambitions, failures, and eccentricities. Central to the narrative is the university's financial struggles and the various schemes proposed to address them, including the secret project involving a hog named Earl Butz. Through a rich tapestry of characters and their interconnected stories, the book humorously critiques the complexities and absurdities of university life, the politics of academia, and the changing landscape of American agriculture.