The novel is a postmodernist narrative that follows the adventures of the reader, who is trying to read a book called "If on a Winter's Night a Traveller." However, the reader keeps encountering obstacles that prevent him from finishing the book, including printer's errors, censorship, and interruptions from other characters. The story is interspersed with the beginnings of ten different novels, each interrupted at a moment of suspense. The book is a meditation on reading, writing, and the nature of narrative itself.

"The Savage Detectives" is a novel that follows the lives of two Latin American poets, Arturo Belano and Ulises Lima, who are founders of a literary movement called "visceral realism." The book is divided into three parts and is narrated by multiple characters, providing different perspectives on the protagonists. The narrative spans over 20 years, following the poets' journey from Mexico City to Europe, Israel, and Africa, as they search for a mysterious poetess and navigate through the world of literature, sex, drugs, and the complexities of life.

This novel is a labyrinthine exploration of identity, madness, and the nature of reality, told through the fragmented narrative of a reclusive man who has lived his life in seclusion on a decrepit estate. As the protagonist delves into his past, he recounts his experiences among the deformed and the destitute, the aristocracy and the servants, while grappling with his own fears and illusions. The narrative weaves a tapestry of grotesque imagery, mythological allusions, and a collapsing social order, challenging the reader to distinguish between truth and fabrication in a world where the boundaries of sanity are blurred.