The novel explores the relationship between two remarkable women: Blanche Wittman, a patient at the Salpêtrière hospital in Paris who became a renowned medium, and Marie Curie, a physicist and chemist who conducted pioneering research on radioactivity. The book delves into their friendship, their scientific collaborations, and the profound impact they had on each other's lives. It also explores the broader themes of scientific discovery, the nature of genius, and the role of women in a male-dominated society.

The novel follows Johann Friedrich Struensee, a German doctor who becomes the personal physician to the mentally ill King of Denmark in the 18th century. Struensee uses his influence to enact Enlightenment-era reforms, but his affair with the Queen and his growing political power lead to his downfall. The book delves into the complexities of power, manipulation, and the human condition, all set against the backdrop of a tumultuous period in Danish history.

The novel is an evocative family saga that spans three generations of women, exploring their lives, struggles, and interconnected stories against the backdrop of Sweden's cultural and social evolution. It delves into the experiences of Hanna and her daughter, Johanna, and granddaughter, Anna, as they navigate the complexities of their relationships, personal identities, and the shifting roles of women through the 20th century. Through their individual journeys, the book addresses themes of love, loss, and the enduring bonds of family, while also painting a vivid portrait of historical events and changes that have shaped the lives of women across generations.