This novel is a gritty, raw portrayal of a group of heroin addicts living in Edinburgh, Scotland. The narrative is non-linear and told from multiple perspectives, providing a deep dive into the minds and lives of these characters. The story explores themes of poverty, addiction, friendship, and the struggle to escape one's circumstances, all set against the backdrop of a bleak urban landscape. It is known for its strong Scottish dialect, graphic content, and dark humor.

The novel is a stream-of-consciousness narrative told from the perspective of Sammy, a shoplifter and ex-convict from Glasgow who wakes up in an alley after a two-day drinking binge to find he is completely blind. As Sammy struggles to navigate his new reality, he contends with bureaucratic systems, confronts his past, and grapples with his relationships, all while trying to understand and adjust to his sudden loss of sight. The story is a gritty exploration of working-class life, the human condition, and the nature of reality.

"Shuggie Bain" is a heart-wrenching tale set in 1980s Glasgow, Scotland, centered on a young boy, Shuggie, who is struggling with his mother's deteriorating mental health and alcoholism. As he tries to navigate his own burgeoning sexuality in a harsh, unforgiving environment, he also strives to care for his mother, who is trapped in a cycle of addiction and abusive relationships. The book gives a stark portrayal of poverty, addiction, love, and the human spirit's resilience.