Set in the universe of Pern, "Nerilka's Story" follows the tale of a young woman from a noble family who is disillusioned with her father's apathy towards a devastating plague. After her family's refusal to aid the suffering population, she takes matters into her own hands, assuming a false identity to distribute medicine and supplies to those in need. Along her journey, she faces challenges and finds herself in the midst of political intrigue, personal growth, and unexpected romance. The story is a testament to courage, compassion, and the resilience of the human spirit in the face of adversity.

In this collection of novellas set within a richly detailed science fiction world, human colonists on the planet Pern face unexpected challenges as they adapt to their new home. The book chronicles the earliest days of the settlement, including the discovery of the deadly Thread which periodically rains from the sky, decimating all organic matter it touches. The settlers must band together, forging a symbiotic relationship with the native dragon-like creatures to combat this threat. As they struggle to survive and maintain their technology-dependent lifestyle, they lay the foundation for the unique society that will define future generations on Pern.