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"Genome organization" as a book category encompasses works that explore how DNA is packaged, arranged, and regulated within cells and across species — from the sequence-level arrangement of genes and regulatory elements to chromatin structure, 3D nuclear architecture (chromosomal territories, loops, topologically associating domains), and their roles in controlling gene expression, development, evolution, and disease. Books in this category may be molecular and mechanistic (detailing nucleosomes, chromatin remodeling, and epigenetic marks), methodological (covering microscopy, chromosome conformation capture, and computational analysis), theoretical or biophysical (models of folding and dynamics), or translational (implications for cancer, congenital disorders, and synthetic biology). The readership ranges from students and researchers in molecular biology, genetics, and bioinformatics to clinicians and informed lay readers interested in how spatial and structural genome features influence function and phenotype.

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