The novel tells the story of Gogol Ganguli, a second-generation Indian-American, who struggles with his unique name and his dual cultural identity. Born to immigrant parents from Kolkata, India, Gogol is named after the famous Russian author, Nikolai Gogol, a decision that shapes his life in unexpected ways. As he grows up, he finds himself torn between his parents' traditional Indian values and his desire to fit into mainstream American society. This internal conflict is further complicated by his relationships with women of different cultural backgrounds. The book explores themes of identity, cultural assimilation, and the immigrant experience.

The book is a chilling tale of horror set in the labyrinthine streets of Calcutta, where an American poet journeys with his wife and infant daughter in search of a legendary poet who has reemerged with new work after years of presumed death. The city's oppressive heat and mystique envelop the family as they become entangled in a nightmarish plot involving a cult dedicated to the goddess Kali, whose followers may have sinister intentions for them. As the protagonist delves deeper into the city's dark underbelly, he is confronted with the true face of evil and must fight to save his loved ones from the clutches of a terrifying power.

The book chronicles the divergent paths of two Bengali brothers whose lives are marked by a tragic event during the tumultuous 1960s in Kolkata. The younger brother becomes involved in the Naxalite movement, leading to his untimely death, while the elder brother, a scientist, migrates to America, carrying the weight of grief and responsibility. The narrative spans across generations, exploring the themes of political activism, family ties, and the immigrant experience as it delves into the enduring effects of loss and the search for identity amidst the crosscurrents of history and culture.