The novel explores the spiritual isolation of misfits and outcasts in a small town of the U.S. South. Its protagonist is a deaf-mute who becomes the confidant for various troubled souls including a black physician, a bitter labor activist, a lonely young girl, and a struggling café owner. Each pours their heart out to him, but he remains unable to respond, reflecting the deep human need for connection and understanding.

Set in the French Riviera in the 1920s, the novel traces the tragic tale of a young psychiatrist, his beautiful wife, and the drama that unfolds amongst their circle of wealthy expatriate friends. The psychiatrist's wife suffers from mental illness, which leads to his own downfall as he struggles to keep his marriage intact and maintain his professional reputation. The narrative explores themes of wealth, love, desire, and the destructive power of obsession, painting a haunting portrait of the dark side of the glamorous Jazz Age.

Set in a bleak New England landscape, the book tells the story of Ethan Frome, a poor, hardworking farmer who is married to a sickly, bitter woman named Zeena. When Zeena's young cousin Mattie comes to live with them, Ethan becomes infatuated with her, leading to a tragic love triangle. The narrative explores themes of passion, duty, and the oppressive nature of rural poverty.

Set in the Harlem of the 1920s, this novel follows the lives of a middle-aged couple, Joe and Violet, and their complicated relationship with a young woman named Dorcas. After Joe starts an affair with Dorcas and later kills her out of jealousy, Violet attempts to disfigure Dorcas's corpse at her funeral out of anger and resentment. The narrative explores themes of love, passion, betrayal, and the transformative power of music, particularly jazz, in a rapidly changing society.

"Fates and Furies" is a novel split into two parts, providing two perspectives on a single marriage. The first half of the book, "Fates," is told from the point of view of the husband, Lotto, a charismatic but failed actor turned successful playwright, who views his marriage as happy and his wife as supportive. The second half, "Furies," is told from the perspective of his wife, Mathilde, revealing her hidden past and the sacrifices and manipulations she has performed to maintain their life together. The novel explores themes of love, secrets, and the different narratives created within a relationship.

This novel follows the lives of three friends in their thirties living in New York City in the months leading up to and following the September 11 attacks. All children of privilege, they struggle with their careers, love lives, and identities against the backdrop of a changing world. The narrative explores themes of entitlement, disillusionment, and the often complicated nature of adult friendships.