The novel follows the life of Patrick Melrose, a man battling with his drug addiction and his troubled relationship with his parents. Patrick tries to come to terms with his mother’s decision to leave her estate to a New Age foundation rather than to him, her only son. The story delves into the complexities of inheritance, parenthood, and the lasting impact of childhood trauma. The narrative shifts between the perspectives of Patrick, his wife, and their two young sons, providing a multi-dimensional view of the family's struggles.

This novel tells the story of a Bangladeshi woman named Nazneen who moves to London at the age of 18 for an arranged marriage to a man 20 years her senior. The narrative explores her life in the city, her struggles with her unhappy marriage, her affair with a young radical, and her attempts to reconcile her traditional upbringing with her new surroundings. The book also explores the lives of immigrants in the UK, the clash of cultures, and the struggle for identity.

This novel presents the intertwined stories of two American academics in London. Virginia Miner, a fifty-something, unmarried tenured professor, is in London for a six-month sabbatical to research children's folk rhymes. Despite her work, she increasingly finds herself drawn into a spiraling relationship with a young man from Oklahoma. In contrast, Fred Turner, a young assistant professor in the English department, leaves his wife and children behind in the States to conduct research on John Gay. He finds himself taken up by the very English and very upscale family of a fellow researcher. Their parallel experiences reflect their shared foreignness and alienation in the UK.

"A Novel About My Wife" is a captivating exploration of a marriage on the brink of collapse. Told from the perspective of the husband, the story delves into the complexities of love, desire, and the secrets that can unravel even the strongest of relationships. As the husband grapples with his own insecurities and suspicions, he becomes consumed by the mystery surrounding his wife's past, leading him down a path of self-discovery and ultimately forcing him to confront the truth about their marriage.

"Holiday" is a novel about Edwin Fisher, a man who is dealing with the recent breakdown of his marriage. In an attempt to find solace and clarity, he decides to spend his holiday alone at a seaside town. Throughout his vacation, he interacts with various characters, each of whom contributes to his journey of self-discovery. The novel explores themes of love, loss, and the complexities of human relationships.