"The Book of Daniel" is a semi-fictional novel that explores the lives of the Isaacson family, specifically focusing on the children, Daniel and Susan, after their parents, accused of being Communists, are executed. The narrative is a combination of historical fiction and a political commentary, providing a deep exploration of the Red Scare in the United States during the Cold War era. The novel is a critical examination of social, political, and familial dynamics in a time of national fear and paranoia.

This novel tells the story of Dr. Wilbur Larch—saint and obstetrician, founder and director of the orphanage in the town of St. Cloud's, Maine, and a man of rare compassion and an addiction to ether. Dr. Larch loves all his orphans, especially Homer Wells, who is never adopted and becomes his invaluable apprentice. As Homer comes of age, he must leave the only home he's ever known to explore the world outside, a world filled with temptations and moral dilemmas, from the struggle over abortion to the question of what constitutes a family.

"Blaming" is a poignant story about a woman named Amy who, after the sudden death of her husband during a holiday, finds herself befriended by an American woman named Martha. Despite their differences, Martha provides Amy with comfort and support, but Amy finds it difficult to accept this kindness due to her reserved and private nature. The novel explores themes of grief, friendship, and the complexities of human relationships, as well as the guilt and blame individuals often place on themselves in times of hardship.

The novel follows the life of twin brothers born from a secret union between an Indian nun and a British surgeon in Ethiopia. Their mother dies during childbirth and their father disappears, leaving them to be raised by two doctors at the mission hospital where they were born. The story spans several decades and continents, and explores themes of love, betrayal, medicine, and the complexity of family ties. One of the brothers, a gifted surgeon, flees to America after a political revolution in Ethiopia, while the other remains and struggles with the challenges of practicing medicine in a developing country.

"Can't We Talk About Something More Pleasant?" is a graphic memoir by Roz Chast that explores her relationship with her aging parents as they approach the end of their lives. Chast uses her signature humor and illustrations to navigate the difficult topics of illness, death, and family dynamics. The book captures the universal experience of caring for aging parents and the emotional toll it can take on adult children.