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Prion diseases is a category for books that explore disorders caused by prions—misfolded, self-propagating proteins—across humans and animals. Works in this category cover the biology and pathophysiology of prions; clinical presentation, diagnosis, and progression of conditions such as Creutzfeldt–Jakob disease, variant CJD, kuru, Gerstmann–Sträussler–Scheinker syndrome, fatal familial insomnia, scrapie, bovine spongiform encephalopathy (mad cow disease), and chronic wasting disease. Titles range from textbooks and research monographs to histories, investigative journalism, and medical narratives, often examining notable outbreaks, surveillance and public health responses, food safety, and policy. Many books also discuss prion-like mechanisms implicated in other neurodegenerative diseases and consider the ethical, social, and economic impacts of these rare but consequential disorders.

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