The novel explores the spiritual isolation of misfits and outcasts in a small town of the U.S. South. Its protagonist is a deaf-mute who becomes the confidant for various troubled souls including a black physician, a bitter labor activist, a lonely young girl, and a struggling café owner. Each pours their heart out to him, but he remains unable to respond, reflecting the deep human need for connection and understanding.

The novel centers on a young boy named Joel Knox who, after his mother's death, is sent to live with his estranged father at a decaying mansion in the rural South. Upon arrival, Joel encounters a bizarre blend of characters, including his morose father, his flamboyant cousin Randolph, and the childlike servant girl, Zoo. As Joel navigates through the eerie and decaying surroundings, he embarks on a journey of self-discovery, confronting secrets about his family and his own identity, ultimately leading to revelations that challenge his understanding of love, sexuality, and acceptance.

This novel tells the story of the Timberlake family, focusing on two sisters, Stanley and Roy. Stanley is a selfish, manipulative woman who abandons her husband for her sister Roy's husband, causing a series of tragic events. Meanwhile, Roy, the more responsible and virtuous sister, must navigate the fallout of Stanley's actions. The book explores themes of family, morality, and the destructive power of selfishness, all set against the backdrop of the American South in the early 20th century.

"Guard of Honor" is a detailed and realistic portrayal of life in a World War II army air forces base. It revolves around the experiences of a disillusioned newspaperman, who is called back into service during World War II. The narrative delves into the complexities of military life, the intricate bureaucracy, racial tensions, and the moral dilemmas faced by those in positions of power during the war. The novel explores the themes of duty, honor, and the harsh realities of war.