The novel revolves around the lives of the Lambert family, an old-fashioned midwestern couple and their three adult children. The parents, Alfred and Enid, are dealing with Alfred's Parkinson's disease and their own marital problems, while their children are each facing their own personal and professional crises. The narrative explores the themes of family dynamics, societal expectations, and the struggles of modern life. The story climaxes with the family's last Christmas together at their childhood home.

The novel follows the life of Patrick Melrose, a man battling with his drug addiction and his troubled relationship with his parents. Patrick tries to come to terms with his mother’s decision to leave her estate to a New Age foundation rather than to him, her only son. The story delves into the complexities of inheritance, parenthood, and the lasting impact of childhood trauma. The narrative shifts between the perspectives of Patrick, his wife, and their two young sons, providing a multi-dimensional view of the family's struggles.

"Seven Years" is a novel about a complex love triangle. The protagonist is a man who's married to a woman he doesn't love, while he's obsessed with another woman who he doesn't understand. The novel explores the themes of love, desire, and the passage of time, as it jumps back and forth between different periods in the protagonist's life. Over the course of seven years, the protagonist grapples with his feelings and the consequences of his actions, leading to a series of dramatic and emotional revelations.

"Lila" is a novel that explores the life of a homeless child during the Great Depression who eventually becomes the wife of an elderly minister. The narrative follows her journey from a life of hardship and neglect to one of stability and love, weaving in themes of grace, redemption, and the transformative power of faith. Through the protagonist's eyes, the reader is invited to grapple with complex questions about existence, suffering, and the nature of God.

"The Position" is a novel that explores the impact of a bestselling sex manual, written by a couple, on their four children. The book, published in the 1970s, includes explicit illustrations of the couple and becomes a cultural phenomenon. The narrative, spanning over three decades, delves into the lives of the children, their struggles with their parents' public sexual revelations, and how it affects their own relationships and identities as they grow into adulthood.