This novel tells the story of Bigger Thomas, a young African-American man living in Chicago's South Side during the 1930s. Bigger's life takes a tragic turn when he accidentally kills a young white woman. The incident leads to his arrest and trial, revealing the deep-seated racial prejudices and injustices prevalent in American society at the time. The narrative explores themes of poverty, systemic racism, fear, and the effects of oppression.

The novel explores the spiritual isolation of misfits and outcasts in a small town of the U.S. South. Its protagonist is a deaf-mute who becomes the confidant for various troubled souls including a black physician, a bitter labor activist, a lonely young girl, and a struggling café owner. Each pours their heart out to him, but he remains unable to respond, reflecting the deep human need for connection and understanding.

The novel is a poignant exploration of the struggles faced by a young African American single mother living in Harlem during the 1940s. It delves into the systemic racism and sexism that constrict her life, as she endeavors to create a better future for her son amidst the poverty, violence, and oppressive social forces of the urban landscape. The narrative follows her tenacious fight against the insurmountable barriers imposed by a society that is indifferent to her dreams and her dignity, painting a vivid portrait of resilience and the human spirit's quest for freedom.

"The Man with the Golden Arm" is a novel that tells the story of Frankie Machine, a talented card dealer and drummer in post-World War II Chicago who becomes addicted to morphine. The narrative vividly portrays his descent into addiction and his struggles with poverty and crime, while also exploring themes of despair, corruption, and redemption. The book is notable for its gritty depiction of life in the urban underbelly and its nuanced characterizations.