The book is a collection of two novellas, both narrated by Buddy Glass, a character who also appears in other works by the same author. The first story, "Raise High the Roof Beam, Carpenters," is set during World War II and focuses on the wedding day of Buddy's older brother Seymour, who fails to show up. The second story, "Seymour, an Introduction," is Buddy's homage to his brother, exploring his character, their relationship, and Seymour's influence on Buddy's life and writing. The book delves into themes of spirituality, family dynamics, and the nature of art and artists.

The book is a poignant tale of two French sisters during World War II who face the brutal German occupation of France in their own unique ways. While one sister joins the Resistance, risking her life to save others, the other struggles to maintain her family's home and protect her daughter, showcasing the resilience and strength of women under the shadow of war. Their paths are fraught with danger, moral complexity, and heartbreaking sacrifices, as they each fight for love, freedom, and survival against the backdrop of a world torn apart by conflict.

The novel is a poignant exploration of the American experience, focusing on two brothers from a small town who find themselves on divergent paths at the dawn of the 21st century. One brother enlists in the military, driven by a sense of duty and the desire for adventure, and is sent to the Middle East, where he confronts the harsh realities of war. Meanwhile, the other brother remains at home, dealing with his own struggles and the impact of his brother's absence on their family. Their journeys reflect the personal and national conflicts of a country grappling with its identity and the consequences of its actions abroad.