Blockbuster Drugs by Jie Jack Li
A concise history of how best-selling medicines were discovered, developed, and commercialized, combining stories of serendipity with the rigor of medicinal chemistry and clinical testing. Through case studies across areas such as cardiovascular disease, ulcers, depression, and high cholesterol, it illuminates mechanisms of action, key structure–activity breakthroughs, and the scientists and strategic decisions behind them. It also explores the economics that fueled the blockbuster era—marketing, patents, and regulation—and explains how patent cliffs, generic competition, and R&D headwinds ultimately challenged the model.
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- Nationality
- American
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- Original Language
- English
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