Seed To Harvest by Octavia E. Butler

A sweeping quartet that follows the origins and aftermath of a deliberate program to create a telepathic elite: an immortal predatory being breeds and shapes human bodies across centuries while a resilient shapeshifter resists and adapts, their actions giving rise to the Patternists, a stratified telepathic society that dominates ordinary humans; later entries explore the fractures caused by a contagious, mutating pathogen and the ethical, social, and personal costs of power, survival, and identity in a remade human future.

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