Especial Predicador by Garth Ennis

Set in a world where divine and earthly realms collide, the story follows a disillusioned preacher who embarks on a quest to find God, who has mysteriously abandoned Heaven. Accompanied by his ex-girlfriend and an Irish vampire, the preacher grapples with his own faith and morality while confronting a series of bizarre and often dangerous adversaries. As he navigates a landscape filled with dark humor, supernatural elements, and philosophical musings, the preacher's journey becomes a profound exploration of belief, redemption, and the human condition.