The novel is a sweeping historical narrative set in ancient Egypt, following the life of a physician named Sinuhe from his humble beginnings to his rise through Egyptian society. As a witness to the political machinations and cultural shifts of his time, Sinuhe encounters love, betrayal, and the complexities of human nature against the backdrop of significant historical events, including the reign of Pharaoh Akhenaten and the religious revolution he instigated. Through his travels and experiences, Sinuhe reflects on the nature of fate, power, and the eternal search for meaning in a changing world.

The novel is a sweeping historical epic set in ancient Egypt, following the life of Sinuhe, a physician who rises from humble beginnings to become a trusted confidant of pharaohs and kings. Through Sinuhe's eyes, readers experience the political intrigue, war, and religious turmoil of the time, as he travels across known civilizations, from Babylon to Crete, engaging with historical figures and experiencing the cultural richness of the era. His personal journey of love, betrayal, and search for meaning is set against the backdrop of the fall of the Egyptian empire, providing a vivid tapestry of the human condition and the ebb and flow of destiny.