The novel is about a Russian émigré, Timofey Pnin, who is a professor at an American college. Pnin struggles with the complexities of life, language, and American culture, while dealing with the traumas of his past in Russia. The book is a series of loosely connected episodes, filled with humor, pathos, and Pnin's endearing confusion. His struggles and triumphs in academia and his search for a home and identity form the crux of the story.

"Zangezi" is a complex avant-garde poem that blends elements of drama and epic literature to explore the themes of language, revolution, and cosmic philosophy. The work is structured around the titular prophet-like figure who communicates with both humans and celestial beings, delivering cryptic and prophetic messages. Through a series of chants, monologues, and dialogues, the text delves into the nature of existence and the power of words, employing a unique linguistic style that reflects the author's fascination with the transformative potential of language and his vision of a future shaped by a universal human culture. The poem is known for its experimental use of sound, language, and its radical departure from traditional narrative forms, reflecting the tumultuous changes of the early 20th century and the search for new means of expression.