Set in Newark, New Jersey, during a polio outbreak in the 1940s, the book follows a dedicated playground director, Bucky Cantor, who remains on duty while many others flee the city. Despite his efforts to keep the children safe, polio begins to affect those around him. As fear and panic spread through the community, Bucky also becomes infected and loses his eyesight. The story is a profound exploration of personal responsibility, duty, and the random, tragic nature of life.

This book provides a comprehensive history of the polio epidemic in America, highlighting the nationwide fear and panic it caused, and the subsequent race to find a cure. It chronicles the journey of scientific discovery, from the early days of the disease, through the development of the Salk and Sabin vaccines, to the eventual eradication of polio. The book also explores the role of politics, philanthropy, and public relations in the fight against polio, and the impact this had on modern medicine and society.