The book is a science fiction tale set in the far future, where humanity has spread across the stars and a young boy from the planet Norstrilia, which is the sole source of an incredibly valuable drug that prolongs life, becomes the wealthiest person in the galaxy due to a quirk in the drug's trade laws. To escape jealous neighbors and to experience life beyond his home, he purchases Earth, a planet that has become a historical theme park. The story weaves through his adventures and misadventures, as he navigates complex societal norms, encounters a variety of unique characters, and grapples with the meaning of wealth, power, and immortality in a universe where every human enhancement is possible, but the essence of humanity is hard to define.

Set in a post-apocalyptic world, the novel explores the lives of survivors after a nuclear catastrophe has ravaged Earth. The story intertwines the fates of various characters, including a phocomelic radio personality who broadcasts from a satellite, a young girl with telepathic abilities, and the eponymous Dr. Bloodmoney, a sinister scientist whose experiments may have contributed to the disaster. As the survivors navigate a transformed society filled with strange mutations and remnants of the past, they confront the challenges of rebuilding civilization and the complexities of human nature in the face of existential threats.

In this science fiction novel, a group of colonists from Earth seek to establish a new society on the distant planet of Pern. As they struggle to adapt to their new environment, they are unprepared for the deadly Thread falling from the sky, which destroys all organic matter it touches. The colonists' survival depends on genetically engineered dragons, created from native lifeforms, which can burn the Thread out of the sky with their fiery breath. The bond between the dragons and their human riders becomes the cornerstone of Pernese society, as they work together to defend their home against the periodic onslaughts. The novel explores themes of pioneering, human ingenuity, and the forging of a symbiotic relationship between humans and dragons in the face of adversity.