The Cahills are a wealthy San Francisco family with twisted secrets. Marla Cahill wakes from a coma after a highway crash with no memory and a reconstructed face while another woman died. Her family calls her Marla, but they are strangers as she recuperates in an isolated mansion and grows increasingly certain she is not who they say and that her life is in danger.

Sisters Cassie and Allie leave Oregon to pursue acting in Los Angeles, but Allie becomes a star while Cassie remains stuck in bit parts. When Allie's body double is shot and Allie goes missing, police trace a last call to Cassie though she has no memory of placing it, and she is confined to a Portland psych ward amid public suspicion. Cassie checks out to find Allie, but macabre murders that mimic her family make her doubt everyone and herself.

A white South African woman fleeing her past sets up a small cake shop in Kigali and, through baking and quiet hospitality, becomes entwined with a diverse circle of neighbors—Rwandan survivors of the 1994 genocide, people living with HIV/AIDS, and other displaced souls—learning to confront grief, guilt and cultural difference while discovering unexpected friendships, love and the slow, fragile work of healing in a country rebuilding itself.