Junk Dna by Nessa Carey

A Journey Through the Dark Matter of the Genome

A clear, accessible tour of the genome’s “dark matter,” arguing that noncoding DNA once dismissed as evolutionary debris actually contains regulatory elements, transposons and epigenetic marks that govern gene expression, development and disease; using experiments and anecdotes it overturns the idea of useless “junk,” explains the molecular mechanisms and evolutionary roles of these sequences, and outlines the medical implications for understanding cancer, inherited disorders and future therapies.

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