Boone's Lick by Larry McMurtry

Set in the mid-19th century, the story follows a determined woman named Mary Margaret Cecil and her family as they embark on a perilous journey from Boone's Lick, Missouri, to Fort Phil Kearny, Wyoming. Accompanied by her children and her brother-in-law, Mary Margaret is in pursuit of her wayward husband, Dick, who has left them to work as a freighter on the frontier. Along the way, they encounter various challenges and colorful characters, reflecting the rugged and often unpredictable nature of life in the American West. The narrative explores themes of family, resilience, and the pursuit of personal fulfillment amidst the backdrop of a rapidly changing nation.